Rab23’s genetic structure, function and related diseases: a review
نویسندگان
چکیده
منابع مشابه
Rab23’s genetic structure, function and related diseases: a review
Rab23 has been proven to play a role in membrane trafficking and protein transport in eukaryotic cells. Rab23 is also a negative regulator of the Sonic hedgehog (Shh) signaling pathway in an indirect way. The nonsense mutation and loss of protein of Rab23 has been associated with neural tube defect in mice and aberrant expression in various diseases in human such as neural system, breast, visce...
متن کاملReview of NKG2D function and its related ligands: review article
The natural killer group 2D (NKG2D) is a transmembrane protein and a member of the CD94/NKG2 family of C-type lectin-like receptors. NKG2D is encoded by the KLRK1 gene, which is located in the NK-gene complex (NKC) placed on chromosomes 6 and 12 in mice and humans, respectively. NKG2D forms a homodimer structure and binds through ectodomains with its related ligands. Each of its monomers consis...
متن کاملA review of neuroblastoma: prevalence, diagnosis, related genetic factors, and treatment
Neuroblastoma is considered as the most common solid tumor in children and it is a special types of nervious cells cancer. Neuroblastoma has high potency for metastasis to other organs such as neck, chest, abdomen, or spine. In this narrative review, we assessed prevalence, diagnosis, related factors, and treatment of neuroblastoma based on published articles from 2007 to 2017. All published a...
متن کاملReview microRNAs and genetic diseases
microRNAs (miRNAs) are a class of small RNAs (19-25 nucleotides in length) processed from double-stranded hairpin precursors. They negatively regulate gene expression in animals, by binding, with imperfect base pairing, to target sites in messenger RNAs (usually in 3' untranslated regions) thereby either reducing translational efficiency or determining transcript degradation. Considering that e...
متن کاملPomegranate: Biodiversity and genetic resources, a review
Pomegranate (Punica granatum L.) is a multipurpose plant that is important as nutrition, medical, horticulture, landscape and environment. The plant has been cultivated since old Iran and Egypt which is mentioned in Bible and Quran. Origin of the plant is Iran and some neighbour countries, although it is cultivated in many countries, now a day. Botanically, it is classified in Punicaceae and ha...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bioscience Reports
سال: 2017
ISSN: 0144-8463,1573-4935
DOI: 10.1042/bsr20160410